Leading-Edge Capabilities

Crystal Reservoir Technology


Minimizing the Amount of Active Pharmaceutical Ingredient

One of the most successful advancements in transdermal drug delivery systems, our Crystal Reservoir Technology has resulted in smaller patches with a more controlled and sustained drug release. This efficient way of releasing a drug is based on the oversaturation of an adhesive polymer with medication, thus forcing a partial crystallization of the drug. The presence of both molecular solute and solid crystal forms allow for a considerably higher concentration and consistent supply of drug in each patch. As the skin absorbs the molecular solute, crystals re-dissolve to maintain maximum thermodynamic activity at the site of contact.

Crystal Reservoir Technology

Crystal Reservoir Technology is based on the oversaturation of an adhesive polymer with medication, thus forcing a partial crystallization of drug. The presence of both molecular solute and solid crystal forms allow for a considerably higher concentration and consistent supply of drug in each patch.


By modifying the concentration of crystals to solute, various patterns of drug release are achieved. The crystal reservoir system can support three patterns of drug release:


 
 
 
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